endocrine
17α-OH-Progesterone
17-OHP
Also known as 17-hydroxyprogesterone
Specification
- Method
- LC-MS/MS — steroid panel Liquid chromatography–tandem mass spectrometry
- Validated matrices
-
- Venous serum Standard draw
- Tasso capillary serum ~600 µL
- Tube
- RED
- CPT
83498- Reportable range
- 3.375 – 300 ng/dL
Clinical utility
Core marker in 21-hydroxylase deficiency. Immunoassay measurement has been shown to read 2–3.5× the structurally verified value.
Published reference ranges
Published values for 17α-OH-Progesterone vary along 4 axes:
- sex
- menstrual cycle phase
- time of day (AM)
- Tanner stage in adolescents
Because a single unstratified figure would misrepresent them, none is shown here.
Published values vary by sex, age, time of collection, menstrual cycle phase and analytical method. The interval applicable to a patient's result appears on that patient's report.